Pharmacokinetics & Pharmacodynamics

Pharmacokinetic is the quantitative analysis of drug movement in, through and out of the body. The intensity of the effect is related to the concentration of the drug at the site of action. Pharmacokinetics also includes the study of the time course of drug absorptiondistributionmetabolism, and excretionClinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient. Primary goals of clinical pharmacokinetics include enhancing safetyefficacy and reducing the toxicity of a patient’s drug therapy. The development of strong correlations between drug concentrations and their pharmacologic responses has enabled clinicians to apply pharmacokinetic principles to actual patient situations. 

Pharmacodynamics is the study of the physiological and biological effect of drugs. The effect of a drug present at the site of achievement is determined by that drug’s binding to a receptor. Receptors may be present on neurons in the central nervous system to depress pain sensation, on cardiac muscle to affect the intensity of contraction, or even within bacteria to disrupt maintenance of the bacterial cell wall.

  • Metal complexes in medicine
  • Bioorganic and Bioinorganic Chemistry
  • Kinetics of drug action in disease
  • Therapeutic drug monitoring
  • Clinical Pharmacokinetics
  • Variation in chemical diversities in drugs

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